1-Bromooctane → HCID 19807838, compound

HRID 867369Notes

Reaction equation

HRID 867369 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([C:14]([OH:16])=[O:15])=[CH:10][CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1.[OH-].[K+].[CH2:19](Br)[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>O>[CH2:19]([O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:9]([C:14]([OH:16])=[O:15])=[CH:10][CH:11]=[CH:12][CH:13]=2)=[CH:6][CH:7]=1)[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]

Participants

5

Reactant 3

HCID 81401-BromooctaneHCID 14797Potassium Hydroxide3×HCID 27593032-(4-hydroxyphenyl)benzoic Acid

Product 1

HCID 19807838HCID 19807838, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.01 mol of 4'-hydroxybiphenylcarboxylic acid and 0.02 mol of potassium hydroxide were dissolved in a mixture of 300 ml of alcohol and 30 ml of water. Then, 1.2 ml of n-octyl bromide was added thereto, and the resultant mixture was refluxed for 12 hours. A 10% potassium hydroxide solution containing 1.12 g of KOH was added and the resultant mixture was refluxed for 2 hours to cause hydrolysis. The product was recrystallized in a mixture of ethanol and glacial acetic acid to obtain 4'-n-octyloxybiphenyl carboxylic acid.

Workup

  1. additionwas added
  2. customhydrolysis
  3. customThe product was recrystallized in a mixture of ethanol and glacial acetic acid

Sources & evidence

ORD record
ord-b88850098b4143be86c7cc541b2069cb
Source dataset
uspto-grants-1988_10
Patent number
US04775223

Reaction notes

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