Choline → HCID 21289647, compound

Participants

Reaction Steps

25 pbw (0.10 mole) of 1-(2,6-diethylphenyl)imidazole-5-carboxylic acid and 27.0 pbw (0.11 mole) of a 50% aqueous solution of choline are heated in 100 pbv of toluene in a water separator, until the water has been completely removed. The mixture is allowed to cool and is then evaporated in vacuo. 34.5 pbw (97% of theory) of 2-hydroxyethyltrimethylammonium 1-(2,6-diethylphenyl)imidazole-5-carboxylate, a high-viscosity oil, are obtained; identification is carried out by 1H-NMR spectroscopy.

Provenance & Evidence