Hydrochloric Acid → HCID 21289657, compound

Participants

Reaction Steps

Dry hydrogen chloride gas was slowly bubbled into a stirred solution of 3.0grams (0.012 mol) of N,N'-dimethyl-N-[ 5-([6-fluorpyridin-2-yl]methyl]thio-1,3,4-thiadiazol-2-yl] urea (prepared by the method of Example 2) dissolved in a mixture of 50 ml of chloroform and 10 ml of diethyl ether over a 5 minute period at room temperature. Theprecipitated solid product was collected by vacuum filtration and dried to yield 3.3 grams of the title compound, m.p. 177°-179° C.

Provenance & Evidence