huagongshe.com
HRID867431

反应详情

EQUATION

反应方程式

HRID 867431 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C#CC(=O)O
HCID371

2-Butynedioic acid

C4H2O4

结构：CCCCCCCCNC(=S)NCCCCCCCC
HCID2758677

N,N'-Dioctylcarbamimidothioic acid

C17H36N2S

PRODUCTS

生成物

1
结构：CCCCCCCCN=C1SC(=CC(=O)O)C(=O)N1CCCCCCCC
HCID53876847

未命名化合物

收率 75.6%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

A mixture of acetylenedicarboxylic acid (7.2 g, 60 mmoles) and N,N'-dioctylthiourea (18 g, 60 mmoles) in methanol (300 mls) is stirred at room temperature for 16 hours. The solvent is removed under reduced pressure to leave a syrupy residue which eventually crystallizes. Recrystallization from acetonitrile gave the product (18 g), mp 57°-61° C.

WORKUP

后处理

  1. customThe solvent is removed under reduced pressure
  2. customto leave a syrupy residue which
  3. customeventually crystallizes
  4. customRecrystallization from acetonitrile