HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Butynedioic acid → [3-Octyl-2-(octylimino)-4-oxo-5-thiazolidinylidene]acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Butynedioic acid | HCID 371 | — |
| Reactant | 1,3-Dioctyl-2-thiourea | HCID 2758677 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | [3-Octyl-2-(octylimino)-4-oxo-5-thiazolidinylidene]acetic acid | HCID 53876847 | 75.6% |
Reaction Steps
A mixture of acetylenedicarboxylic acid (7.2 g, 60 mmoles) and N,N'-dioctylthiourea (18 g, 60 mmoles) in methanol (300 mls) is stirred at room temperature for 16 hours. The solvent is removed under reduced pressure to leave a syrupy residue which eventually crystallizes. Recrystallization from acetonitrile gave the product (18 g), mp 57°-61° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04775677 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-03714de898a947d290e9ed74c8d2d0f4 |
| Source note | uspto-grants-1988_10 |