2-Butynedioic acid → HCID 54134383, compound

HRID 867432Notes

Reaction equation

HRID 867432 reaction equation
[CH2:1]([NH:3][C:4]([NH:6][CH2:7][CH3:8])=[S:5])[CH3:2].[C:9]([C:14](O)=[O:15])#[C:10][C:11]([OH:13])=[O:12]>>[CH2:1]([N:3]1[C:14](=[O:15])[C:9](=[CH:10][C:11]([OH:13])=[O:12])[S:5][C:4]1=[N:6][CH2:7][CH3:8])[CH3:2]

Participants

3

Reactant 2

HCID 3712-Butynedioic acidHCID 2735009N,N'-Diethylthiourea

Product 1

HCID 54134383HCID 54134383, compoundYield 82.1%

Procedure

Prepared by the method described in Example 1 from N,N'-diethylthiourea (1.0 g, 8 mmoles) and acetylenedicarboxylic acid (1 g, 9 mmoles). Crystallization from hexane gave the product (1.5 g), mp 148°-152° C.

Workup

  1. customPrepared by the method
  2. customCrystallization from hexane

Sources & evidence

ORD record
ord-404d504856bc4cbbaa79131d07a3383a
Source dataset
uspto-grants-1988_10
Patent number
US04775677

Reaction notes

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