Isopropylamine → HCID 131715727, compound

HRID 867828Notes

Reaction equation

HRID 867828 reaction equation
[CH:1]([NH2:4])([CH3:3])[CH3:2].[CH2:5]([S:12][C:13]1[CH:21]=[CH:20][C:16]([C:17]([OH:19])=[O:18])=[C:15]([C:22]2[NH:23][C:24](=[O:31])[C:25]([CH:28]([CH3:30])[CH3:29])([CH3:27])[N:26]=2)[N:14]=1)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>CCOCC.O1CCCC1>[CH:1]([NH3+:4])([CH3:3])[CH3:2].[CH2:5]([S:12][C:13]1[CH:21]=[CH:20][C:16]([C:17]([O-:19])=[O:18])=[C:15]([C:22]2[NH:23][C:24](=[O:31])[C:25]([CH:28]([CH3:29])[CH3:30])([CH3:27])[N:26]=2)[N:14]=1)[C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][CH:11]=1

Participants

5

Reactant 2

HCID 6363IsopropylamineHCID 13799415HCID 13799415, compound

Product 1

HCID 131715727HCID 131715727, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 8028TetrahydrofuranSolvent

Procedure

0.16 g (2.7 mmol) isopropylamine are added to a solution of 1.0 g (2.7 mmol) 6-benzylthio-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-nicotinic acid in 50 ml ether and 50 ml tetrahydrofuran. The sediment is sucked off and dried.

Workup

  1. customdried

Sources & evidence

ORD record
ord-997aff61ec92409eae5562b84a3dc6df
Source dataset
uspto-grants-1988_10
Patent number
US04776876

Reaction notes

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