HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxymethyl-5-methyl-6-piperidinopyrimidine → 4-Hydroxymethyl-5-methyl-6-morpholinopyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxymethyl-5-methyl-6-piperidinopyrimidine | HCID 14306161 | — |
| Reactant | 4-Methoxymethyl-5-methyl-6-morpholinopyrimidine | HCID 21245797 | — |
| Product | 4-Hydroxymethyl-5-methyl-6-morpholinopyrimidine | HCID 14306166 | — |
Reaction Steps
Substituting 4-methoxymethyl-5-methyl-6-morpholinopyrimidine, (5.77 g), for 4-methoxymethyl-5-methyl-6-piperidinopyrimidine and using corresponding molar proportions of the other reagents in the method of Example 10(iv), gave 4-hydroxymethyl-5-methyl-6-morpholinopyrimidine, 3.46 g, m.p. 66°-68°, from petroleum ether (40/60).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04777172 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-98eff9ca92a44a3599bf3b432168b09b |
| Source note | uspto-grants-1988_10 |