Isaglidole → HCID 70407469, compound

HRID 867895Notes

Reaction equation

HRID 867895 reaction equation
[F:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][N:5]([NH:11][C:12]1[NH:13][CH2:14][CH2:15][N:16]=1)[CH2:6]2.[C:17]([OH:24])(=[O:23])/[CH:18]=[CH:19]\[C:20]([OH:22])=[O:21]>C(OCC)(=O)C>[C:17]([OH:24])(=[O:23])/[CH:18]=[CH:19]\[C:20]([OH:22])=[O:21].[F:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH2:4][N:5]([NH:11][C:12]1[NH:13][CH2:14][CH2:15][N:16]=1)[CH2:6]2

Participants

4

Reactant 2

HCID 183683IsaglidoleHCID 444266Maleic Acid

Product 1

HCID 70407469HCID 70407469, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

2.0 g of the base (Example 1) are dissolved in 100 ml of hot ethyl acetate and a hot solution of 1 g of maleic acid in ethyl acetate is added.

Sources & evidence

ORD record
ord-15cfdb73000b452c9a5f0276fdb5ba78
Source dataset
uspto-grants-1988_10
Patent number
US04777181

Reaction notes

Loading…