HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyridineethanamine → 1,8,8-Trimethyl-3-[2-(2-pyridinyl)ethyl]-3-azabicyclo[3.2.1]octane-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyridineethanamine | HCID 75919 | — |
| Reactant | 1,8,8-Trimethyl-3-oxabicyclo[3.2.1]octane-2,4-dione | HCID 94834 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 1,8,8-Trimethyl-3-[2-(2-pyridinyl)ethyl]-3-azabicyclo[3.2.1]octane-2,4-dione | HCID 14235066 | — |
Reaction Steps
A mixture of (-) camphoric anhydride 5 g (0.029 mol), 2-(2-aminoethyl)pyridine 3.6 (0.03 mol) and 50 ml of pyridine was refluxed overnight. The solvent is removed under reduced pressure and the remaining oil boiled in 20 ml of ethanol and allowed to cool.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04777254 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-14d27eb0342e4f14801d1f2da1572273 |
| Source note | uspto-grants-1988_10 |