Chlorosuccinimide → HCID 13822062, compound

HRID 867947Notes

Reaction equation

HRID 867947 reaction equation
[CH2:1]([N:5]1[C:10]([CH3:11])=[CH:9][C:8](=[O:12])[C:7]([C:13]([NH:15][C:16]2[C:21]([CH2:22][CH3:23])=[CH:20][CH:19]=[CH:18][C:17]=2[CH2:24][CH3:25])=[O:14])=[C:6]1[CH3:26])[CH2:2][CH2:3][CH3:4].[Cl:27]N1C(=O)CCC1=O>C(Cl)(Cl)Cl>[CH2:1]([N:5]1[C:10]([CH3:11])=[C:9]([Cl:27])[C:8](=[O:12])[C:7]([C:13]([NH:15][C:16]2[C:17]([CH2:24][CH3:25])=[CH:18][CH:19]=[CH:20][C:21]=2[CH2:22][CH3:23])=[O:14])=[C:6]1[CH3:26])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 31398Chlorosuccinimide2×HCID 13745359HCID 13745359, compound

Product 1

HCID 13822062HCID 13822062, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A mixture of 500 mg (1.41 mmol, m.p. 110°-112° C.) of 1-butyl-N-(2,6-diethylphenyl)-1,4-dihydro-2,6-dimethyl-4-oxo-3-pyridinecarboxamide and 188 mg (1.41 mmol) of N-chlorosuccinimide was dissolved in 15 ml of chloroform and refluxed with stirring. To the reaction mixture, 190 mg of N-chloro-succinimide was added in twice, and refluxed for 15.2 hours.

Workup

  1. temperaturerefluxed
  2. temperaturerefluxed for 15.2 hours

Sources & evidence

ORD record
ord-7018d06336c447b8bb76b49c45ffcf35
Source dataset
uspto-grants-1988_10
Patent number
US04777256

Reaction notes

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