Bromine → HCID 14257702, compound

Participants

Reaction Steps

7,8-Dichloro-6-methoxy-1-tetralone (2.7 g, 0.011 mole) was suspended in acetic acid (45 ml) warmed slightly with stirring, and 0.57 ml of bromine in 5 ml of acetic acid was added over a 20 minute time period. The reaction mixture was stirred for 10 minutes, and then poured into 200 ml of stirred ice water. A white solid was filtered from the reaction mixture, dissolved in ether (75 ml), washed with brine, dried over MgSO4, evaporated in vacuo and directly used in the next step.

Provenance & Evidence