Hydrochloric Acid → HCID 13851841, compound

HRID 868007Notes

Reaction equation

HRID 868007 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[CH2:10][CH:9]([C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH2:8][C:7]2=O)([O-])=O.[ClH:20]>>[ClH:20].[NH2:1][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[CH2:10][CH:9]([C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH2:8][CH2:7]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 13488726HCID 13488726, compound

Product 1

HCID 13851841HCID 13851841, compound

Procedure

Ethyl 6-nitro-1,2,3,4-tetrahydro-4-oxo-2-naphthalenecarboxylate was treated according to the procedure described in step (1) of Referential Example 1 but using concentrated hydrochloric acid instead of 48% hydrobromic acid to give ethyl 6-amino-1,2,3,4-tetrahydro-2-naphthalenecarboxylate hydrochloride with m.p. 117°-130° C. (decomposition).

Sources & evidence

ORD record
ord-8ad6c214a2ed4da39d6f848ff4ea8b72
Source dataset
uspto-grants-1988_10
Patent number
US04777257

Reaction notes

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