HCID 21289506, compound → HCID 21289505, compound

HRID 868021Notes

Reaction equation

HRID 868021 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][C:8]2[CH2:17][CH2:16][C:15]3[CH:14]=[C:13]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[CH:12]=[CH:11][C:10]=3[CH:9]=2)[CH:2]=1>C(O)C.[C].[Pd]>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][CH:8]2[CH2:17][CH2:16][C:15]3[CH:14]=[C:13]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[CH:12]=[CH:11][C:10]=3[CH2:9]2)[CH:2]=1

Participants

4

Reactant 1

HCID 21289506HCID 21289506, compound

Product 1

HCID 21289505HCID 21289505, compoundYield 99.3%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

1.8 g of ethyl 6-(3-pyridylmethyl)-7,8-dihydro-2-naphthalenecarboxylate was dissolved in 100 ml of ethanol and 1 g of 10% palladium carbon was added thereto. The mixture was catalytically reduced. After absorption of hydrogen gas was completed, the catalyst was removed by filtration. The filtrate was concentrated in vacuo to give 1.8 g of ethyl 6-(3-pyridylmethyl)-5,6,7,8-tetrahydro-2-naphthalenecarboxylate as an oil.

Workup

  1. customAfter absorption of hydrogen gas
  2. customthe catalyst was removed by filtration
  3. concentrationThe filtrate was concentrated in vacuo

Sources & evidence

ORD record
ord-567dd333a0aa4a88a90c93d7c9b0f635
Source dataset
uspto-grants-1988_10
Patent number
US04777257

Reaction notes

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