Phosphorus pentachloride → HCID 14278970, compound

Participants

Reaction Steps

To a suspension of 4-oxo-7,8-bis(phenylmethoxy)-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid (1.21 g, 3.0 mmol) in 30 ml of dichloromethane was added 0.69 g (3.3 mmol) of phosphorous pentachloride at 0° C. After stirring for 90 minutes, the solid was filtered off, washed with dichloromethane and dried in vacuo. Yield: 0.91 g; melting point 152.4° C.

Provenance & Evidence