Oxalyl chloride → Acetyl chloride, (benzoyloxy)-

HRID 868190Notes

Reaction equation

HRID 868190 reaction equation
[C:1]([O:9][CH2:10][C:11]([OH:13])=O)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(Cl)(=O)C([Cl:17])=O>C(Cl)(Cl)Cl>[C:1]([O:9][CH2:10][C:11]([Cl:17])=[O:13])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 65578Oxalyl chloride2×HCID 12647149HCID 12647149, compound

Product 1

HCID 10888895Acetyl chloride, (benzoyloxy)-

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

4.1 g (0.023 m) Benzoyloxy acetic acid (as synthesized in Example XIII) was combined with 2.96 ml (4.3 g, 0.032 m) oxalyl chloride in 50 ml petroleum ether. This was stirred under a CaSO4 drying tube for 5 hrs., at which time 2.0 ml more oxalyl chloride and 50 ml chloroform were added. The reaction was stirred overnight.

Workup

  1. stirringThe reaction was stirred overnight

Sources & evidence

ORD record
ord-9f193701636d40df9f6068968c6d3028
Source dataset
uspto-grants-1988_10
Patent number
US04778618

Reaction notes

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