Hydroxyamine hydrochloride → 4-Ethyl2-hydroxyimino-5-nitro-hexanamide

HRID 868233Notes

Reaction equation

[CH2:1]([CH:3]([CH:10]([N+:12]([O-:14])=[O:13])[CH3:11])[CH2:4][C:5](=O)[C:6]([NH2:8])=[O:7])[CH3:2].Cl.[NH2:16][OH:17]>>[CH2:1]([CH:3]([CH:10]([N+:12]([O-:14])=[O:13])[CH3:11])[CH2:4][C:5](=[N:16][OH:17])[C:6]([NH2:8])=[O:7])[CH3:2]

Participants

Reactant 2

HCID 443297Hydroxyamine hydrochloride

HCID 14329816HCID 14329816, compound

Product 1

HCID 867424064-Ethyl2-hydroxyimino-5-nitro-hexanamideYield 69.8%

Procedure

4-Ethyl-2-hydroxyimino-5-nitro-hexanamide (15 mg) was prepared in the substantially same manner as that of Example 24 from 4-ethyl-5-nitro-2-oxo-hexanamide (20 mg) and hydroxylamine hydrochloride (14 mg).

Sources & evidence

ORD record: ord-caa50524de9849c3bfb073a02d753689
Source dataset: uspto-grants-1988_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04778804

Reaction notes

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