Hydrochloric Acid → 7677-21-6

A 1000 ml four-neck flask equipped with a reflux condenser, mechanical stirrer, thermometer and a dropping funnel was charged with 187.8 g (1.0 mole) of a 61.9 percent aqueous solution of N,N,N',N'-tetramethyl-1,2-ethanediamine. The solution was cooled with an ice-water bath and 197.1 g (2 moles) of 37 percent hydrochloric acid was added at such a rate as to keep the temperature below 45° C. To the well-agitated N,N,N',N'-tetramethyl-1,2-ethanediamine dihydrochloride solution so obtained, 185.0 g (2.0 moles) of epichlorohydrin was added slowly, taking care that the temperature did not exceed 45° C. After the addition was completed, the temperature was raised to between 60° and 70° C. for 30 minutes. A 65.7 percent aqueous solution of the title compound was obtained.

1. customA 1000 ml four-neck flask equipped with a reflux condenser, mechanical stirrer
2. temperatureThe solution was cooled with an ice-water bath
3. customthe temperature below 45° C

ORD record

ord-230f5fbf10d44f249fa5dde1eb8a0019

Source dataset

uspto-grants-1988_10

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04778813