Benzyl Bromide → HCID 21288490, compound

HRID 868423Notes

Reaction equation

HRID 868423 reaction equation
[CH2:1](Br)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:9][CH:10]([C:16]1[CH:17]=[C:18]([CH:20]=[CH:21][CH:22]=1)[NH2:19])[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]>>[OH:9][CH:10]([C:16]1[CH:17]=[C:18]([CH:20]=[CH:21][CH:22]=1)[NH:19][CH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 21280500HCID 21280500, compound

Product 1

HCID 21288490HCID 21288490, compound

Procedure

For compounds in which X is --NR2 --(CHR1)n --, the corresponding amino starting compounds are employed to form the desired amino compound. Thus, aniline is condensed with 3-(1-hydroxyhexyl)benzylbromide to form 2-[3-(1-hydroxyhexyl)benzylamino]benzene. Alternatively, benzyl bromide is condensed with 3-(1-hydroxyhexyl)aniline to form 2-[3-(1-hydroxyhexyl)anilinomethyl]benzene.

Sources & evidence

ORD record
ord-92042b8a8b384e9c9c692acae5cb02c7
Source dataset
uspto-grants-1988_10
Patent number
US04778931

Reaction notes

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