Cyclopentylamine → N-(4-Chloro-2-methoxyphenyl)-1-ethyl[1,2,4]triazolo [4,3-a]quinoxalin-4-amine

HRID 868523Notes

Reaction equation

Cl[C:2]1[C:3]2[N:4]([C:12]([CH2:15][CH3:16])=[N:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH3:17][O:18][C:19]1[CH:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:20]=1[NH2:26].C1(N)CCCC1>>[Cl:25][C:23]1[CH:22]=[CH:21][C:20]([NH:26][C:2]2[C:3]3[N:4]([C:12]([CH2:15][CH3:16])=[N:13][N:14]=3)[C:5]3[C:10]([N:11]=2)=[CH:9][CH:8]=[CH:7][CH:6]=3)=[C:19]([O:18][CH3:17])[CH:24]=1

Participants

Reactant 3

HCID 2906Cyclopentylamine

HCID 7143Benzenamine, 4-chloro-2-methoxy-

HCID 133857064-Chloro-1-ethyl[1,2,4]triazolo[4,3-a]quinoxaline

Product 1

HCID 14280618N-(4-Chloro-2-methoxyphenyl)-1-ethyl[1,2,4]triazolo [4,3-a]quinoxalin-4-amine

Procedure

The title compound was prepared essentially as described in Example 2 substituting 4-chloro-1-ethyl [1,2,4]triazolo[4,3-a]quinoxaline and 2-methoxy-4-chlorobenzenamine for 4-chloro-1-methyl1,2,4]triazolo[4,3-a]quinoxaline and cyclopentanamine respectively; mp 245°-248° C.

Sources & evidence

ORD record: ord-95fcb4094a8d49c4b95d3b9a29b11f07
Source dataset: uspto-grants-1988_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04780464

Reaction notes

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