HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isatin → 1-(3-Diisopropylaminopropyl)isatin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isatin | HCID 7054 | — |
| Reactant | 3-Diisopropylaminopropyl chloride hydrochloride | HCID 19743095 | — |
| Product | 1-(3-Diisopropylaminopropyl)isatin | HCID 13934420 | 72.9% |
Reaction Steps
By using isatin and 3-diisopropylaminopropyl chloride hydrochloride, a method analogous to that described in Reference Example 1 was carried out, and the reaction product was purified with silica gel column chromatography (eluent: chloroform/methanol=50/1) and then recrystallized from hexane to obtain 1-(3-diisopropylaminopropyl)isatin having a melting point of 49°-50° C. (yield: 72.9%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04780477 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-17f06082b51d423c9d8188a986b8a5b2 |
| Source note | uspto-grants-1988_10 |