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HRID868560

反应详情

EQUATION

反应方程式

HRID 868560 的结构方程式

REACTANTS

反应物

2
结构：O=C1Nc2ccccc2C1=O
HCID7054

Isatin

C8H5NO2

结构：CC(C)N(CCCCl)C(C)C.Cl
HCID19743095

3-Chloro-N,N-di(propan-2-yl)propan-1-amine--hydrogen chloride (1/1)

C9H21Cl2N

PRODUCTS

生成物

1
结构：CC(C)N(CCCN1C(=O)C(=O)c2ccccc21)C(C)C
HCID13934420

未命名化合物

收率 72.9%

PROCEDURE

实验过程

By using isatin and 3-diisopropylaminopropyl chloride hydrochloride, a method analogous to that described in Reference Example 1 was carried out, and the reaction product was purified with silica gel column chromatography (eluent: chloroform/methanol=50/1) and then recrystallized from hexane to obtain 1-(3-diisopropylaminopropyl)isatin having a melting point of 49°-50° C. (yield: 72.9%).

WORKUP

后处理

  1. customthe reaction product was purified with silica gel column chromatography (eluent: chloroform/methanol=50/1)
  2. customrecrystallized from hexane