Thionyl Chloride → HCID 12841523, compound

Participants

Reaction Steps

6.0 Grams of the above alcohol compound obtained was dissolved in 100 ml of dry benzene, and to this solution was added dropwise 3.2 ml of thionyl chloride with stirring at room temperature. The mixture was heated under refulx for 4 hours. The reaction mixture was concentrated under reduced pressure, and the residue was triturated with diethyl ether. The precipitated crystals were collected by filtration to obtain 7.4 g of 2-(N-isopropylcyclohexylamino)ethyl chloride hydrochloride having a melting point of 99°-103° C.

Provenance & Evidence