Semicarbazide hydrochloride → HCID 178457221, compound

HRID 868588Notes

Reaction equation

HRID 868588 reaction equation
[CH:1]([N:4]([CH:19]([CH3:21])[CH3:20])[CH2:5][CH:6]([N:8]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:11](=O)[C:9]1=[O:10])[CH3:7])([CH3:3])[CH3:2].Cl.[NH2:23][NH:24][C:25]([NH2:27])=[O:26]>>[CH:1]([N:4]([CH:19]([CH3:21])[CH3:20])[CH2:5][CH:6]([N:8]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)/[C:11](=[N:23]\[NH:24][C:25]([NH2:27])=[O:26])/[C:9]1=[O:10])[CH3:7])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 11236Semicarbazide hydrochlorideHCID 13934421HCID 13934421, compound

Product 1

HCID 178457221HCID 178457221, compoundYield 65.3%

Procedure

By using 1-(2-diisopropylamino-1-methylethyl)isatin and semicarbazide hydrochloride, a method analogous to that described in Example 10 was carried out and the reaction product was recrystallized from ethanol to obtain (E)-1-(2-diisopropylamino-1-methylethyl)isatin 3-semicarbazone having a melting point of 195°-197° C. (yield: 65.3%).

Workup

  1. customthe reaction product was recrystallized from ethanol

Sources & evidence

ORD record
ord-b160d800078c407a9cbd12b8d2d6877e
Source dataset
uspto-grants-1988_10
Patent number
US04780477

Reaction notes

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