4-Benzylsemicarbazide hydrochloride → HCID 178422543, compound

HRID 868591Notes

Reaction equation

HRID 868591 reaction equation
[CH:1]([N:4]([CH:19]([CH3:21])[CH3:20])[CH2:5][CH2:6][N:7]1[C:17]2[C:12](=[CH:13][C:14]([CH3:18])=[CH:15][CH:16]=2)[C:10](=O)[C:8]1=[O:9])([CH3:3])[CH3:2].Cl.[CH2:23]([NH:30][C:31](=[O:34])[NH:32][NH2:33])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:23]([NH:30][C:31](=[O:34])[NH:32]/[N:33]=[C:10]1/[C:8](=[O:9])[N:7]([CH2:6][CH2:5][N:4]([CH:19]([CH3:21])[CH3:20])[CH:1]([CH3:3])[CH3:2])[C:17]2[C:12]/1=[CH:13][C:14]([CH3:18])=[CH:15][CH:16]=2)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 124017124-Benzylsemicarbazide hydrochlorideHCID 13934409HCID 13934409, compound

Product 1

HCID 178422543HCID 178422543, compoundYield 74.6%

Procedure

By using 1-(2-diisopropylaminoethyl)-5-methylisatin and 4-benzylsemicarbazide hydrochloride, a method analogous to that described in Example 6 was carried out to obtain (E)-1-(2-diisopropylaminoethyl)5-methylisatin 3-(4-benzylsemicarbazone) having a melting point of 159°-160° C. (yield: 74.6%, recrystallizing solvent: ethanol).

Sources & evidence

ORD record
ord-be2b3e13291749fd80e07041e1736677
Source dataset
uspto-grants-1988_10
Patent number
US04780477

Reaction notes

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