HuagongsheHuagongshe Chemistry Print Report · For research reference only
Semicarbazide hydrochloride → [(E)-[1-[3-[di(propan-2-yl)amino]propyl]-5-methyl-2-oxoindol-3-ylidene]amino]urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Semicarbazide hydrochloride | HCID 11236 | — |
| Reactant | 1-(3-Diisopropylaminopropyl)-5-methylisatin | HCID 13934423 | — |
| Product | [(E)-[1-[3-[di(propan-2-yl)amino]propyl]-5-methyl-2-oxoindol-3-ylidene]amino]urea | HCID 178422539 | 72.2% |
Reaction Steps
By using 1-(3-diisopropylaminopropyl)-5-methylisatin and semicarbazide hydrochloride, a method analogous to that described in Example 4 was carried out to obtain (E)-1-(3-diisopropylaminopropyl)-5-methylisatin 3-semicarbazone having a melting point of 145°-148° C. (yield: 72.2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04780477 |
| Source dataset | uspto-grants-1988_10 |
| ORD ID | ord-9bcdc69cddfc49f480b9b80b300c4af4 |
| Source note | uspto-grants-1988_10 |