Semicarbazide hydrochloride → HCID 178449090, compound

HRID 868606Notes

Reaction equation

[C:1]([NH:5][CH2:6][CH2:7][N:8]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:11](=O)[C:9]1=[O:10])([CH3:4])([CH3:3])[CH3:2].Cl.[NH2:20][NH:21][C:22]([NH2:24])=[O:23]>>[C:1]([NH:5][CH2:6][CH2:7][N:8]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)/[C:11](=[N:20]\[NH:21][C:22]([NH2:24])=[O:23])/[C:9]1=[O:10])([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 11236Semicarbazide hydrochloride

HCID 13934424HCID 13934424, compound

Product 1

HCID 178449090HCID 178449090, compoundYield 40.3%

Procedure

By using 1-(2-tert-butylaminoethyl)isatin and semicarbazide hydrochloride, a method analogous to that described in Example 10 was carried out, and the reaction product was recrystallized from ethanol to obtain (E)-1-(2-tert-butylaminoethyl)isatin 3-semicarbazone having a melting point of 173°-176° C. (decomposition) (yield: 40.3%).

Workup

customthe reaction product was recrystallized from ethanol

Sources & evidence

ORD record: ord-7f8a52b057344d39bc796f90cad73cee
Source dataset: uspto-grants-1988_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04780477

Reaction notes

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