Ethanol → HCID 135617149, compound

HRID 868609Notes

Reaction equation

HRID 868609 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH2:8][C:9]([OH:11])=[O:10])[CH:5]=[CH:6][CH:7]=1.[Cl:12][C:13]1[CH:14]=[CH:15][C:16]([OH:21])=[C:17]([CH:20]=1)[CH:18]=O.C(O)C>CO>[Cl:12][C:13]1[CH:14]=[CH:15][C:16]([OH:21])=[C:17]([CH:20]=1)[CH:18]=[N:1][C:2]1[CH:3]=[C:4]([CH2:8][C:9]([OH:11])=[O:10])[CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 124815-Chloro-salicylaldehydeHCID 571807(3-Aminophenyl)acetic acid

Product 1

HCID 135617149HCID 135617149, compoundYield 69.6%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Using the procedure of Sheeman et al [J.A.C.S., Vol. 84, (1982), p. 2457], 1.5 g of 3-amino-phenylacetic acid, 1.72 g of 5-chloro-2-hydroxy-benzaldehyde, 480 ml of 100% ethanol and 35 ml of methanol were reacted to obtain 2 g of 3-[(5-chloro-2-hydroxy-benzylidene)-amino]-phenylacetic acid.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-e3f23a4fdd774b15b8fdf7211d3fc8d4
Source dataset
uspto-grants-1988_10
Patent number
US04780504

Reaction notes

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