6-Methylbenzofuran → HCID 14257620, compound

HRID 868613Notes

Reaction equation

HRID 868613 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]2[CH:6]=[CH:7][O:8][C:4]=2[CH:3]=1.[H][H]>CO.[Pd]>[CH3:1][C:2]1[CH:10]=[CH:9][C:5]2[CH2:6][CH2:7][O:8][C:4]=2[CH:3]=1

Participants

5

Reactant 2

HCID 869296-MethylbenzofuranHCID 178418361HCID 178418361, compound

Product 1

HCID 14257620HCID 14257620, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

6-Methylbenzofuran (15 g) was dissolved in methanol (200 ml) containing 0.5 g of 10% palladium on carbon. This solution was shaken on a Paar hydrogenator under hydrogen at 40 psi. When hydrogen uptake was complete, the solution was filtered through Celite and the ethanol evaporated to yield 6-methyl-2,3-dihydrobenzofuran.

Workup

  1. filtrationthe solution was filtered through Celite
  2. customthe ethanol evaporated

Sources & evidence

ORD record
ord-1957b114f40e408c93883833b0b7ccc0
Source dataset
uspto-grants-1988_10
Patent number
US04780480

Reaction notes

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