Dichloromethane → HCID 21268692, compound

HRID 868627Notes

Reaction equation

HRID 868627 reaction equation
[CH3:1][S:2][C:3]1[CH:22]=[CH:21][C:6]([CH2:7][C:8]2[C:16]3[O:15][CH:14]=[CH:13][C:12]=3[CH:11]=[C:10]([CH2:17][C:18](O)=[O:19])[CH:9]=2)=[CH:5][CH:4]=1.[Cl:23]CCl.S(Cl)(Cl)=O>CN(C)C=O>[CH3:1][S:2][C:3]1[CH:22]=[CH:21][C:6]([CH2:7][C:8]2[C:16]3[O:15][CH:14]=[CH:13][C:12]=3[CH:11]=[C:10]([CH2:17][C:18]([Cl:23])=[O:19])[CH:9]=2)=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 21268696HCID 21268696, compound

Product 1

HCID 21268692HCID 21268692, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 7-(4-methylthiobenzyl)benzofuran-5-ylacetic acid (10 g), dichloromethane (100 ml), thionyl chloride (10.0 ml) and dimethylformamide (0.2 ml) was stirred at room temperature for 6 hours. The solvent was then evaporated to give a residue which contained the title compound.

Workup

  1. customThe solvent was then evaporated
  2. customto give a residue which

Sources & evidence

ORD record
ord-ceac71860c824b89b49d8c3c50a65a1e
Source dataset
uspto-grants-1988_10
Patent number
US04780480

Reaction notes

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