HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 71295146, compound → HCID 68008520, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 71295146 | HCID 71295146 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68008520 | HCID 68008520 | 92.8% |
Reaction Steps
174 mg of 5-(3,6-dihydro-2H-pyran-4-yl)-2-nitropyridine are hydrogenated using 100 mg of 5% Pd/C and hydrogen in 10 ml of tetrahydrofuran. The mixture is filtered off and evaporated in a rotary evaporator, giving 138 mg of 5-(3,6-dihydro-2H-pyran-4-yl)pyridin-2-ylamine crude product, which is reacted further above purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969335B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-d88a68c2922446a8a39eeb55ac0194d8 |
| Source note | uspto-grants-2015_03 |