Dichloromethane → 1-(2,6-Dichlorophenyl)-3-[6-methoxy-7-(6-methylamino-1-hexynyl)quinazolin-4-yl]urea
Reaction equation
[CH2:48]([Cl:49])[Cl:50].[Cl:1][c:2]1[c:3]([NH:9][C:10](=[O:11])[NH:12][c:13]2[n:14][cH:15][n:16][c:17]3[cH:18][c:19]([C:25]#[C:26][CH2:27][CH2:28][CH2:29][CH2:30][N:31]([CH3:32])[NH:33][C:34]([O:35][C:36]([CH3:37])([CH3:38])[CH3:39])=[O:40])[c:20]([O:23][CH3:24])[cH:21][c:22]23)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[OH:41][C:42]([C:43]([F:44])([F:45])[F:46])=[O:47]>>[Cl:1][c:2]1[c:3]([NH:9][C:10](=[O:11])[NH:12][c:13]2[n:14][cH:15][n:16][c:17]3[cH:18][c:19]([C:25]#[C:26][CH2:27][CH2:28][CH2:29][CH2:30][NH:31][CH3:32])[c:20]([O:23][CH3:24])[cH:21][c:22]23)[c:4]([Cl:8])[cH:5][cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-57007cf95a1c4733b5f12f6123a9b5a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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