Hydrochloric Acid → HCID 70114827, compound

HRID 868969Notes

Reaction equation

HRID 868969 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=[CH:3][C:2]=1[CH2:11][CH2:12][C:13]1[N:25]=[C:16]2[CH:17]=[CH:18][C:19]3[C:24]([N:15]2[N:14]=1)=[CH:23][CH:22]=[CH:21][N:20]=3.[ClH:26]>CO>[ClH:26].[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[N:4]=[CH:3][C:2]=1[CH2:11][CH2:12][C:13]1[N:25]=[C:16]2[CH:17]=[CH:18][C:19]3[C:24]([N:15]2[N:14]=1)=[CH:23][CH:22]=[CH:21][N:20]=3

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 70114444HCID 70114444, compound

Product 1

HCID 70114827HCID 70114827, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 2-(2-(quinoxalin-2-yl)ethyl)-[1,2,4]triazolo[1,5-a][1,5]naphthyridine (15 mg, 0.046 mmol) in 1 N HCl in methanol was stirred at room temperature for 10 min. The solvent was removed under reduce pressure to give 18 mg of 2-(2-(quinoxalin-2-yl)ethyl)-[1,2,4]triazolo[1,5-a][1,5]naphthyridine hydrochloride as a yellow solid. MS (ESI): m/z 327.1 [M+H]+.

Workup

  1. customThe solvent was removed

Sources & evidence

ORD record
ord-834a53897a2b48ceab7a1a401a7715cc
Source dataset
uspto-grants-2015_03
Patent number
US08969349B2

Reaction notes

Loading…