Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Lithium Chloride → HCID 178509968, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Lithium Chloride | HCID 433294 | — |
| 반응물 | 2-Fluoro-4-iodobenzonitrile | HCID 2774518 | — |
| 반응물 | HCID 178418918 | HCID 178418918 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | HCID 178509968 | HCID 178509968 | — |
반응 단계
To a stirred solution of 4-iodo-2-fluorobenzonitrile (2.5 g, 10.12 mmol) in 10.12 ml THF under argon, a solution of isopropylmagnesium chloride. LiCl in THF (10.12 ml, 13.16 mmol) was added at 0° C. The reaction mixture was stirred at this temperature for 5 min to afford the title compound, which was used immediately in the next step as a stock solution (˜0.5M in THF).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08969341B2 |
| 출처 데이터셋 | uspto-grants-2015_03 |
| ORD ID | ord-97e332776eee4adda06df08c52199f0f |
| 출처 메모 | uspto-grants-2015_03 |