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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 869080생성일: 2026년 10월 25일

Lithium Chloride → HCID 178509968, 화합물

https://huagongshe.com/reaction/869080

반응식

참여 물질

역할이름HCID투입량
반응물Lithium ChlorideHCID 433294—
반응물2-Fluoro-4-iodobenzonitrileHCID 2774518—
반응물HCID 178418918HCID 178418918—
용매TetrahydrofuranHCID 8028—
생성물HCID 178509968HCID 178509968—

반응 단계

To a stirred solution of 4-iodo-2-fluorobenzonitrile (2.5 g, 10.12 mmol) in 10.12 ml THF under argon, a solution of isopropylmagnesium chloride. LiCl in THF (10.12 ml, 13.16 mmol) was added at 0° C. The reaction mixture was stirred at this temperature for 5 min to afford the title compound, which was used immediately in the next step as a stock solution (˜0.5M in THF).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08969341B2
출처 데이터셋uspto-grants-2015_03
ORD IDord-97e332776eee4adda06df08c52199f0f
출처 메모uspto-grants-2015_03