Dichloromethane → 4'-[[2-n-Propyl-4-methyl-6-(imidazo[1,2-a]pyrimidin-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylic acid

HRID 86923Notes

Reaction equation

HRID 86923 reaction equation
[CH2:1]([CH2:2][CH3:3])[c:4]1[n:5][c:6]2[c:7]([n:8]1[CH2:9][c:10]1[cH:11][cH:12][c:13](-[c:16]3[c:17]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[cH:18][cH:19][cH:20][cH:21]3)[cH:14][cH:15]1)[cH:29][c:30](-[c:34]1[n:35][c:36]3[n:37]([cH:38][cH:39][cH:40][n:41]3)[cH:42]1)[cH:31][c:32]2[CH3:33].[CH2:50]([Cl:51])[Cl:52].[OH:43][C:44]([C:45]([F:46])([F:47])[F:48])=[O:49]>>[CH2:1]([CH2:2][CH3:3])[c:4]1[n:5][c:6]2[c:7]([n:8]1[CH2:9][c:10]1[cH:11][cH:12][c:13](-[c:16]3[c:17]([C:22](=[O:23])[OH:24])[cH:18][cH:19][cH:20][cH:21]3)[cH:14][cH:15]1)[cH:29][c:30](-[c:34]1[n:35][c:36]3[n:37]([cH:38][cH:39][cH:40][n:41]3)[cH:42]1)[cH:31][c:32]2[CH3:33]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 19965039HCID 19965039, compound

Product 1

HCID 199647344'-[[2-n-Propyl-4-methyl-6-(imidazo[1,2-a]pyrimidin-2-yl)-benzimidazol-1-yl]-methyl]-biphenyl-2-carboxylic acid

Sources & evidence

ORD record
ord-641b79e828e846e38b5a20ac1e95d1da
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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