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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 86931Generated: October 30, 2026

Bicarbonate Ion → Methyl 8-[1-[3,5-bis(trifluoromethyl)phenyl]ethyl-methylcarbamoyl]-7-(4-fluoro-2-methylphenyl)-1,8-diazaspiro[4.5]decane-2-carboxylate

https://huagongshe.com/reaction/86931

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriethylsilaneHCID 12052—
ReactantHCID 178501806HCID 178501806—
ProductMethyl 8-[1-[3,5-bis(trifluoromethyl)phenyl]ethyl-methylcarbamoyl]-7-(4-fluoro-2-methylphenyl)-1,8-diazaspiro[4.5]decane-2-carboxylateHCID 76692592—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-681edeb37799459a8234fdf713c906ce
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)