反应详情

温度

70 °C

To the compound obtained by Example 2-39 step (i) (300 mg) in acetonitrile (5 ml) was added 2-aminoethanol (265 mg) and heated at 70° C. for 24 hours. The reaction mixture was purified by column chromatography (ethyl acetate:7N ammonia-methanol 95:5) to give the titled compound. Yield: 295 mg (100%).

1. customThe reaction mixture was purified by column chromatography (ethyl acetate:7N ammonia-methanol 95:5)