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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 869375Generated: October 29, 2026

2-Hydroxybenzonitrile → 1-(3-Amino-4-chlorobenzo[B]thiophen-2-YL)ethanone

https://huagongshe.com/reaction/869375

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-HydroxybenzonitrileHCID 11907—
Reactant2-Chloro-6-sulfanylbenzonitrileHCID 21224765—
Product1-(3-Amino-4-chlorobenzo[B]thiophen-2-YL)ethanoneHCID 12614640—

Reaction Steps

The procedure was similar to step S1A, while the starting material was 2-chloro-6-mercapto-benzonitrile (2A) in stead of 2-hydroxy-benzonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969373B2
Source datasetuspto-grants-2015_03
ORD IDord-df4e7cfff2e7493caad3d35683dfb269
Source noteuspto-grants-2015_03