HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 86722237, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-Thiazolecarboxaldehyde, 2-(1-methylethyl)- (9CI) | HCID 45083848 | — |
| Reactant | HCID 86722235 | HCID 86722235 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 86722237 | HCID 86722237 | — |
Reaction Steps
7G (3 g, 12.5 mmol) was dissolved in THF (tetrahydrofuran, 30 mL). To the solution was added 2-isopropyl-thiazole-5-carbaldehyde (2.33 g, 15 mmol, 1.2 eq), followed by crushed NaOH powder (1 g, 25 mmol, 2 eq). The reaction mixture was stirred at room temperature for 10 min. The solution became dark and some solids formed. The mixture was poured into ice-water under stirring.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969373B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-271882d0b4f7420ea38dd17a9b13c444 |
| Source note | uspto-grants-2015_03 |