反应详情

11B (0.73 g, 3 mmol) was dissolved in THF (14 mL). To the solution was added LiBH4 (0.23 g, 10 mmol) in batches at room temperature. The reaction mixture was refluxed overnight, then quenched with 14 mL of anhydrous MeOH and concentrated to dryness. The residue was dissolved in dichloromethane and filtered. The filtrate was concentrated and dried to give a crude product 11C (0.48 g, 100% yield).

1. temperatureThe reaction mixture was refluxed overnight
2. customquenched with 14 mL of anhydrous MeOH
3. concentrationconcentrated to dryness
4. dissolutionThe residue was dissolved in dichloromethane
5. filtrationfiltered
6. concentrationThe filtrate was concentrated
7. customdried