HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68893980, compound → HCID 86721380, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68893980 | HCID 68893980 | — |
| Reactant | (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile | HCID 86721333 | — |
| Product | HCID 86721380 | HCID 86721380 | 74% |
Reaction Steps
[step 2] Using 2-propyl-1H-imidazo[4,5-b]pyrazine (68 mg, 0.42 mmol) obtained in step 1 and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (153 mg, 0.43 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (136 mg, 74%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969345B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-90d185bc31df435fa6c6892bd6d8336f |
| Source note | uspto-grants-2015_03 |