HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 596076, compound → HCID 86721439, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 596076 | HCID 596076 | — |
| Reactant | (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile | HCID 86721333 | — |
| Product | HCID 86721439 | HCID 86721439 | 91% |
Reaction Steps
[step 2] Using 4,5-dichloro-2-isopropyl-1H-imidazole (68 mg, 0.381 mmol) obtained in step 1 and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (130 mg, 0.363 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (150 mg, 91%) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08969345B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-7c737d2e2156466e920b7bb11a95bb78 |
| Source note | uspto-grants-2015_03 |