Water → 1-Benzyl-3-methyl-4-(4-trifluoromethylbenzofur-7-yl)-1,2,3,6-tetrahydropyridine

HRID 86961Notes

Reaction equation

HRID 86961 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH3:28])[C:11]([c:14]2[cH:15][cH:16][c:17]([C:23]([F:24])([F:25])[F:26])[c:18]3[cH:19][cH:20][o:21][c:22]23)([OH:27])[CH2:12][CH2:13]1.[OH2:29].[c:30]1([CH3:31])[cH:32][cH:33][c:34]([S:35]([OH:36])(=[O:37])=[O:38])[cH:39][cH:40]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH3:28])[C:11]([c:14]2[cH:15][cH:16][c:17]([C:23]([F:24])([F:25])[F:26])[c:18]3[cH:19][cH:20][o:21][c:22]23)=[CH:12][CH2:13]1

Participants

4

Reactant 3

HCID 962WaterHCID 6101p-Toluenesulfonic acidHCID 224956381-Benzyl-3-methyl-4-hydroxy-4-(4-trifluoromethylbenzofur-7-yl)piperidine

Product 1

HCID 224956981-Benzyl-3-methyl-4-(4-trifluoromethylbenzofur-7-yl)-1,2,3,6-tetrahydropyridine

Sources & evidence

ORD record
ord-f39302979a55493bb56ecec0c5ace805
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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