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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 869665Generated: October 30, 2026

Indole-2-carboxylic acid → HCID 178431203, compound

https://huagongshe.com/reaction/869665

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndole-2-carboxylic acidHCID 72899—
ReactantHCID 66961881HCID 66961881—
ReactantHCID 178525710HCID 178525710—
ProductHCID 178431203HCID 178431203—

Reaction Steps

The title compound was prepared according to the procedure described in Step 3 of EXAMPLE 1 using 5-chloro-3-((3-methylpyrrolidin-3-yl)methoxy)picolinonitrile dihydrochloride (EXAMPLE 84, Step 4) and trans-4-(trifluoromethyl)cyclohexanecarboxylic acid instead of (R)-3-(pyrrolidin-2-ylmethoxy)picolinamide dihydrochloride and indole-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08969383B2
Source datasetuspto-grants-2015_03
ORD IDord-5141ec599d3f49acbd4451237e0d22c6
Source noteuspto-grants-2015_03