Water → HCID 86674511, compound

Participants

Reaction Steps

A suspension of 3-(5,7-dichloropyrazolo[1,5-a]pyrimidin-2-yl)-6-fluoro-2-methylquinoxaline (157 mg, 0.451 mmol) in N,N-dimethylformamide (4.0 mL), 1-amino-2-methyl-propan-2-ol (48 mg, 0.541 mmol), and potassium carbonate (187 mg, 1.35 mmol) was stirred at room temperature for 2 h. The reaction mixture was poured into ice-cooled water, and the resulting precipitate was collected and washed with water to give 1-{[5-chloro-2-(7-fluoro-3-methylquinoxalin-2-yl)pyrazolo[1,5-a]pyrimidin-7-yl]amino}-2-methylpropan-2-ol. MS (APCI): m/z 401/403 (M+H).

Provenance & Evidence