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HRID870044

反应详情

EQUATION

反应方程式

HRID 870044 的结构方程式

REACTANTS

反应物

1
结构：COC(=O)c1ccc([C@H](C)NC(=O)c2csc(Br)c2Cc2cccc(Cl)c2)cc1
HCID57900972

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](NC(=O)c1csc(Br)c1Cc1cccc(Cl)c1)c1ccc(C(=O)O)cc1
HCID24952578

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCC.CCOC(C)=O
溶剂HCID21226206

未命名化合物

PROCEDURE

实验过程

Methyl 4-[(S)-1-({[5-bromo-4-(3-chlorobenzyl)-3-thienyl]carbonyl}amino)ethyl]benzoate from Example 4, Step 1 (25.0 mg, 0.0507 mmol) was reacted under conditions similar to Example 1, Step 11. After trituration of the crude product in 1:1 EtOAc/hexane, the desired product was obtained as an off-white solid. MS (−APCI): m/z 476 (M−1)−.