Hydrochloric Acid → HCID 178524960, compound

Participants

Reaction Steps

Stir a 90° C. solution of 1-benzyl-5-hydroxy-1H-1,2,3-triazole-4-carboxylate (1.46 g; 1.0 equiv; 5.90 mmoles) and sodium hydroxide (1N; 10.00 mL; 1.7 equiv; 10.00 mmoles) for 9 hours. Add 1N hydrochloric acid until the pH is 2, then filter the reaction and dry the filter cake to afford 1-benzyl-5-hydroxy-1H-1,2,3-triazole-4-carboxylic acid (1.15 g; 89%): MS (m/z): 220(M+1).

Provenance & Evidence