Phthalimide → HCID 86696456, compound

HRID 870749Notes

Reaction equation

HRID 870749 reaction equation
[CH2:1]([N:6]1[C:10](=[O:11])[CH2:9][CH2:8][C@H:7]1[CH2:12][N:13]1C(=O)C2C(=CC=CC=2)C1=O)[CH2:2][CH:3]([CH3:5])[CH3:4].C1(=O)NC(=O)C2=CC=CC=C12>>[NH2:13][CH2:12][C@H:7]1[N:6]([CH2:1][CH2:2][CH:3]([CH3:4])[CH3:5])[C:10](=[O:11])[CH2:9][CH2:8]1

Participants

3

Reactant 2

HCID 6809PhthalimideHCID 89802608HCID 89802608, compound

Product 1

HCID 86696456HCID 86696456, compoundYield 100%

Procedure

The (S)-2-((1-isopentyl-5-oxopyrrolidin-2-yl)methyl)isoindoline-1,3-dione was subjected to the phthalimide deprotection procedure described in example 5.6.123, Part B, to obtain 100% yield of the desired product.

Sources & evidence

ORD record
ord-5c330b43b465411eaead4e1bb25979e9
Source dataset
uspto-grants-2015_03
Patent number
US08969565B2

Reaction notes

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