Hydrochloric Acid → HCID 86696471, compound

Participants

Reaction Steps

Concentrated hydrochloric acid (3.0 mL) was added to a solution of tert-butyl 4-(3-bromoimidazo[1,2-b]pyridazin-6-yl)-3-methylpiperazine-1-carboxylate (1.2 g, 3.1 mmol) in methanol (60 mL) and allowed to stir at ambient temperature under N2 blanket for 3d. The solution was then evaporated to dryness to provide 1.1 g of light brown solid. LRMS (ESI) m/z 295.9/297.9 [(M+H)]+, calc'd for C11H14BrN5. 296.17.

Provenance & Evidence