Hydrazine hydrate (1:1) → HCID 86696493, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 3-bromo-6-fluoroimidazo[1,2-b]pyridazine (2.16 g, 10 mmol) in hydrazine monohydrate (10 mL) was heated at 70° C. for 30 minutes. The mixture was cooled to room temperature, and the titled compound (1.78 g) was collected by filtration. 1H NMR (400 MHz, DMSO-d6) δ ppm 4.27 (br. s., 2H) 6.78 (d, J=9.60 Hz, 1H) 7.51 (s, 1H) 7.73 (dd, J=9.60, 1.52 Hz, 1H) 8.20 (br. s., 1H).

Provenance & Evidence